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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
11.52
Human Site:
S2506
Identified Species:
21.11
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S2506
L
R
E
N
L
R
R
S
Q
Q
A
Q
D
T
S
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S2506
L
R
E
N
L
R
R
S
Q
Q
A
Q
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S2506
L
R
E
N
L
R
R
S
Q
Q
A
Q
D
T
S
Dog
Lupus familis
XP_852631
1216
141588
E1025
N
I
F
S
L
I
Q
E
K
N
E
L
Q
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
H2282
L
R
E
N
L
R
G
H
Q
Q
A
Q
D
T
S
Rat
Rattus norvegicus
Q7TSP2
1385
159522
D1194
A
E
I
L
R
M
K
D
Q
L
C
E
M
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
R1959
E
H
Q
E
E
Q
L
R
K
L
K
E
E
L
R
Frog
Xenopus laevis
NP_001080954
2954
339950
A2678
L
K
E
E
L
R
R
A
Q
A
D
N
D
T
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
L1822
L
Q
E
T
K
E
Q
L
K
K
T
L
E
N
N
Honey Bee
Apis mellifera
XP_001121311
1418
164919
K1227
I
T
T
I
L
K
N
K
C
D
L
L
S
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
Q2324
K
T
K
V
K
D
A
Q
E
K
V
E
C
Q
A
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
R1056
T
K
A
M
S
E
A
R
N
E
L
E
S
C
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
S1157
L
S
K
E
L
A
S
S
N
R
W
Q
D
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
100
6.6
N.A.
86.6
6.6
N.A.
N.A.
0
53.3
N.A.
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
26.6
N.A.
N.A.
33.3
73.3
N.A.
N.A.
53.3
20
N.A.
33.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
16
8
0
8
31
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
8
8
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
8
8
0
47
0
0
% D
% Glu:
8
8
47
24
8
16
0
8
8
8
8
31
16
16
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
16
16
0
16
8
8
8
24
16
8
0
0
0
0
% K
% Leu:
54
0
0
8
62
0
8
8
0
16
16
24
0
8
0
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
8
% M
% Asn:
8
0
0
31
0
0
8
0
16
8
0
8
0
8
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
8
16
8
47
31
0
39
8
8
0
% Q
% Arg:
0
31
0
0
8
39
31
16
0
8
0
0
0
8
16
% R
% Ser:
0
8
0
8
8
0
8
31
0
0
0
0
16
0
31
% S
% Thr:
8
16
8
8
0
0
0
0
0
0
8
0
0
39
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _